Διεθνής Δημοσιεύσεις

Revisiting the use of the EORTC QLQSTO22 to assess healthrelated quality of life of patients with gastric cancer: incorporating updated treatment options and crosscultural perspectives

S. C. Sodergren, A. HurleyWallace, V. Vassiliou, B. Alkhaffaf, B. Batsaikhan, A. S. Darlington, T. FleitasKanonnikof, M. G. Guren, M. Honda, Y. W. Kim, S. Kim, M. N. Krishnamurthy, S. Y. Loh, N. S. Turhal, J. Zhou, K. Dennis, R. Krishnatry, M. Terashima, G. Tsironis, T. Yoshikawa, M. Terada, On behalf of the EORTC Quality of Life Group

Gastric Cancer

https://doi.org/10.1007/s10120-024-01492-8 10 March 2024


Screening, Diagnosis and Treatment of Thyroid Cancer

Frangos S, Life | Special Issue  

Why should we be concerned about a “g”?

Frangos S, Buscombe JR.
Eur J Nucl Med Mol Imaging 2019;46:519

Theragnostics: A neologism that generates schism. The Hellenic thesis.

Frangos S, Giannoula E, Buscombe JR, Iakovou I.
J Nucl Med 2021; 62

Applying thyroid cancer guidelines: a difficult task

Frangos S, Giannoula E, Exadaktylou P, Iakovou I.
Clin Transl Imaging 2021; 9:203-207

The Future of the Past Is the Present: The Role of the UEMS/EBNM in the Current Challenge of Educating Nuclear Medicine Specialists

Frangos S, Hustinx R, Boubaker A, Varetto T, Prior JO, Siroos M, Maffioli L. T. J
Nucl Med 2018;59:396-398

Acknowledging gray areas: 2015 vs. 2009 American Thyroid Association differentiated thyroid cancer guidelines on ablating putatively low-intermediate-risk patients

Frangos S, Iakovou IP, Marlowe RJ, Eftychiou N, Patsali L, Vanezi A, et al.
Eur J Nucl Med Mol Imaging. 2017 Feb;44(2):185-189

Difficulties in deciding whether to ablate patients with putatively "low-intermediate-risk" differentiated thyroid carcinoma: do guidelines mainly apply in the centres that produce them? Results of a retrospective, two-centre quality assurance study

Frangos S, Iakovou IP, Marlowe RJ, Eftychiou N, Patsali L, Vanezi A, Savva A, Mpalaris V, Giannoula EI.
Eur J Nucl Med Mol Imaging. 2015 Dec;42(13):2045-55

EANM Executive Committee. European Association of Nuclear Medicine: adapt the present, shape the future

Frangos S, Knapp WH;
Eur J Nucl Med Mol Imaging. 2014 Mar;41(3):590-1

To be "Padhied": A Neologism to Show the Pathos of Prof. Ajit Padhy for Nuclear Medicine

Frangos S. 
World J Nucl Med. 2014 Jan;13(1):1-2. doi: 10.4103/1450-1147.138566. PMID: 25191104; PMCID: PMC4149762

Prof. Ajit Padhy MBBS, MNAMS, FAMS

Frangos, S., Buscombe, J.
Eur J Nucl Med Mol Imaging 41, 185–186 (2014). https://doi.org/10.1007/s00259-013-2567-8

Subacute thyroiditis after the third dose of the COVID-19 mRNA vaccine. Case report

Frangos, S., Haralambous, H., Michael, K., & Economides, P. A. (2022)
Hellenic journal of nuclear medicine, 25(2), 210-212.

Theragnostics before we found its name

Modoni S, Frangos S, Iakovou I, Boero M, Mansi L.
Q J Nucl Med Mol Imaging 2021;65:000-000. DOI : 10.23736/S1824-4785.21.03410-5

A randomized controlled trial for the use of thymus honey in decreasing salivary gland damage following radioiodine therapy for thyroid cancer: research protocol

Charalambous A, Frangos S, Talias M.
J Adv Nurs. 2014 Jul;70(7):1663-71


Increase in thyroid cancer (TC) incidence in Cyprus: Overdiagnosis or true increase of clinically relevant TC?

Charalambous HC, Demetriou A, Frangos S, Pavlou P.
Ann Oncol 2018;29


Clinical Studies of Nonpharmacological Methods to Minimize Salivary Gland Damage after Radioiodine Therapy of Differentiated Thyroid Carcinoma: Systematic Review Christou A, Papastavrou E, Merkouris A, Frangos S, Tamana P, Charalambous A.
Evid Based Complement Alternat Med. 2016;2016:6795076

lobal Issues of Radiopharmaceutical Access and Availability: A Nuclear Medicine Global Initiative Project

Cutler CS, Bailey E, Kumar V, Schwarz SW, Bom H-S, Hatazawa J, Paez D, Orellana P, Louw L, Mut F, Kato H, Chiti A, Savvas Frangos, Fahey F, Dillehay G, Oh SJ, Lee DS, Lee S-T, Nunez-Miller R, Bandhopadhyaya G, Pradhan PK, Scott AM.
G. J Nucl Med 2021; 62:422-430

WARMTH Thyroid Group. The World Association of Radiopharmaceutical and Molecular Therapy position statement on the initial radioiodine therapy for differentiated thyroid carcinoma

Dizdarevic S, Tulchinsky M, McCready VR, Mihailovic J, Vinjamuri S, Buscombe JR, Lee ST, Frangos S, Sathekge M, Siraj Q, Choudhury P, Bom H, Franceschi M, Ugrinska A, Paez D, Hussain R, Mailman J, Luster M, Virgolini I;
World J Nucl Med. 2019;18:123-126

Multiple endocrine neoplasia 2 in Cyprus: evidence for a founder effect

Fanis P, Skordis N, Frangos S. et al.
J Endocrinol Invest 2018; 41:1149–1157

Ecological Study on Thyroid Cancer Incidence and Mortality in Association with European Union Member States’ Air Pollution

Giannoula E, Melidis C, Frangos S, Papadopoulos N, Koutsouki G, Iakovou I.
Int J Environ Res 2021;18:153

The impact of two scatter correction methods on I-131 AC-SPECT images using an anthropomorphic phantom with variable sizes of thyroid remnants

Hadjiconstanti A, Michael K, Leontiou T, Lontos A, Frangos S, Demosthenous G, Lyra M, Parpottas Y.
Proceedings by ACM: ICBBE2020, 13pp, paper ID: N0032, (ISBN: 978-1-4503-8822-1)


Positron emission tomography in breast cancer: 18F- FDG and other radiopharmaceuticals

Iakovou I, Giannoula E, Gkantaifi A, Levva S, Frangos S.
European J Hybrid Imaging 2018; 2:20

First steps in an uncharted territory by WFNMB

Lee DS, Trujillo PB, Frangos S. 
Eur J Nucl Med Mol Imaging 2019;46:524-530

Lymph node metastasis and extrathyroidal extension in papillary thyroid microcarcinoma in Cyprus: Suspicious subcentimeter nodules should undergo FNA when multifocality is suspected

Papaioannou C, Lamnisos D, Kyriacou K, Lyssiotis T, Constantinides V, Frangos S, Economides A, Economides PA.
J Thyroid Res 2020

"Response of calcitonin levels due to positron emission tomography with (18) F-FDG."

Strauss, Ludwig G.,Savvas Frangos, and Antonia Dimitrakopoulou-Strauss
Hellenic journal of nuclear medicine 15.3 (2012): 251

EANM and the EANM Thyroid Committee. The 2015 Revised American Thyroid Association guidelines for the management of medullary thyroid carcinoma: the "evidence-based" refusal to endorse them by EANM due to the "not evidence-based" marginalization of the role of Nuclear Medicine

Treglia G, Aktolun C, Chiti A, Frangos S, Giovanella L, Hoffmann M, Iakovou I, Mihailovic J, Krause BJ, Langsteger W, Verburg FA, Luster M;
Eur J Nucl Med Mol Imaging. 2016 Jul;43(8):1486-90

Bone metastases: assessment of therapeutic response through radiological and nuclear medicine imaging modalities

Vassiliou V, Andreopoulos D, Frangos S, Tselis N, Giannopoulou E, Lutz S.
Clin Oncol (R Coll Radiol). 2011 Nov;23(9):632-45

EANM and the EANM Thyroid Committee. Why the European Association of Nuclear Medicine has declined to endorse the 2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer

Verburg FA, Aktolun C, Chiti A, Frangos S, Giovanella L, Hoffmann M, Iakovou I, Mihailovic J, Krause BJ, Langsteger W, Luster M;
Eur J Nucl Med Mol Imaging. 2016 Jun;43(6):1001-5


Oxaliplatin-based adjuvant chemotherapy in older patients with stage III colon cancer: an ACCENT/IDEA pooled analysis of 12 trials. Claire Gallois1, Qian Shi2, Levi D. Pederson 2, Thierry André3, Timothy J. Iveson4, Alberto F. Sobrero5, Steven Alberts6, Aimery de Gramont7, Jeffrey A. Meyerhardt8, Thomas George9, Hans-Joachim E. Schmoll10, Ioannis Souglakos11, Andrea Harkin12, Roberto Labianca13, Frank A. Sinicrope6, Eiji Oki14, Anthony F. Shields15, Ioannis Boukovinas16, Rachel Kerr17, Sara Lonardi18, Greg Yothers19, Takayuki Yoshino20, Richard M. Goldberg21, Julien Taieb1, Demetris Papamichael22*

J Clin Oncol In Press


Prognostic Factors Influencing Survival in Ovarian Cancer Patients: A 10-Year Retrospective Study.

Andreou M, Kyprianidou M, Cortas C, Polycarpou I, Papamichael D, Kountourakis P, Giannakou K.Cancers (Basel). 2023 Dec 5;15(24):5710. doi: 10.3390/cancers15245710.PMID: 38136256 Free PMC article.


Leucovorin and Fluorouracil With or Without Oxaliplatin as First-Line Treatment in Advanced Colorectal Cancer.

de Gramont A, Figer A, Seymour M, Homerin M, Hmissi A, Cassidy J, Boni C, Cortes-Funes H, Cervantes A, Freyer G, Papamichael D, Le Bail N, Louvet C, Hendler D, de Braud F, Wilson C, Morvan F, Bonetti A.J Clin Oncol. 2023 Nov 20;41(33):5080-5089. doi: 10.1200/JCO.22.02773.PMID: 37967516


A systematic review and network meta-analysis of randomised controlled trials comparing neoadjuvant treatment strategies for stage II and III rectal cancer.

Simillis C, Khatri A, Dai N, Afxentiou T, Jephcott C, Smith S, Jadon R, Papamichael D, Khan J, Powar MP, Fearnhead NS, Wheeler J, Davies J.Crit Rev Oncol Hematol. 2023 Mar;183:103927. doi: 10.1016/j.critrevonc.2023.103927. Epub 2023 Jan 24.PMID: 36706968 Review.


Prognostic Impact of Early Treatment and Oxaliplatin Discontinuation in Patients With Stage III Colon Cancer: An ACCENT/IDEA Pooled Analysis of 11 Adjuvant Trials.

Gallois C, Shi Q, Meyers JP, Iveson T, Alberts SR, de Gramont A, Sobrero AF, Haller DG, Oki E, Shields AF, Goldberg RM, Kerr R, Lonardi S, Yothers G, Kelly C, Boukovinas I, Labianca R, Sinicrope FA, Souglakos I, Yoshino T, Meyerhardt JA, André T, Papamichael D, Taieb J.J Clin Oncol. 2023 Feb 1;41(4):803-815. doi: 10.1200/JCO.21.02726. Epub 2022 Oct 28.PMID: 36306483


Is cancer biology different in older patients?

Van Herck Y, Feyaerts A, Alibhai S, Papamichael D, Decoster L, Lambrechts Y, Pinchuk M, Bechter O, Herrera-Caceres J, Bibeau F, Desmedt C, Hatse S, Wildiers H.Lancet Healthy Longev. 2021 Oct;2(10):e663-e677. doi: 10.1016/S2666-7568(21)00179-3. Epub 2021 Sep 29.



Latest clinical research in leptomeningeal disease (LMD) - a narrative review
Adrian Wai Chan, Henry C. Y. Wong, Martin Taphoorn, Linda Dirven, Emilie Le Rhun, Hany Soliman, Eva Oldenburger, Srinivas Raman, Vassilios Vassiliou, Pierluigi Bonomo, Michael Koller, Gustavo Nader Marta, Agata Rembielak, Shing Fung Lee, Edward Chow, Charles B. Simone II

New Insights in the Era of Clinical Biomarkers as Potential Predictors of Systemic Therapy-Induced Cardiotoxicity in Women with Breast Cancer: A Systematic Review

Alexia Alexandraki, Elisavet Papageorgiou, Marina Zacharia, Kalliopi Keramida, Andri Papakonstantinou, Carlo M. Cipolla, Dorothea Tsekoura, Katerina Naka, Ketti Mazzocco, Davide Mauri, Manolis Tsiknakis, Georgios C. Manikis, Kostas Marias, Yiola Marcou, Eleni Kakouri, Ifigenia Konstantinou, Maria Daniel, Myria Galazi, Effrosyni Kampouroglou, Domen Ribnikar, Cameron Brown, Georgia Karanasiou, Athos Antoniades, Dimitrios Fotiadis, Gerasimos Filippatos and Anastasia Constantinidou
Cancers 2023, 15, 3290. doi.org/10.3390/cancers15133290

Barriers and facilitators for adopting healthy lifestyles in breast cancer survivors: a scoping review protocol

Ao Shi, King Hei Anthony Fong, Carrie Rodomar, Christiana A. Demetriou, Ourania Kolokotroni, Elena Philippou, Pascale Salameh, Maria Cecilia Mosquera, Elisavet Papageorgiou, Elena Critselis, Yiola Marcou, Constantina Constantinou, Annalisa Quattrocchi
PROOF - SCOPING REVIEW PROTOCOL, 2023, JBI Evid Synth 2023; 21(8):1–9.


A critical appraisal of the four systematic reviews and meta-analysis on stereotactic body radiation therapy versus external beam radiotherapy for painful bone metastases and where we go from here

Henry C. Y. Wong, Adrian Wai Chan, Peter Johnstone, Charles B. Simone II, Inmaculada Navarro-Domenech, Peter Hoskin, Candice Johnstone, Abram Recht, Johan Menten, Yvette M. van der Linden, Joanne M. van der Velden, Quynh-Nhu Nguyen, Stephen Lutz, Nicolaus Andratschke, Jonas Wilmann, Joanna Kazmierska, Mateusz Spalek, Fiona Lim, H. Michael Yu, Brad Perez, Gustavo Nader Marta, Vassilios Vassiliou, Shing Fung Lee, Pierluigi Bonomo, Agata Rembielak, Edward Chow, Eva Oldenburger, Srinivas Raman
Annals of Palliative Medicine (APM), May 2023 - Manuscript ID: APM-23-218


International validation of the EORTC QLQ-ANL27, a field study to test the anal cancer-specific health-related quality of life questionnaire
Samantha C Sodergren, Colin D Johnson, Alexandra Gilbert, Anne-Sophie Darlington, Kim Cocks, Marianne G Guren, Eleonor Rivin del Campo, Christine Brannan, Peter Christensen, William Chu, Hans Chung, Kristopher Dennis, Isacco Desideri, Duncan C Gilbert, Rob Glynne-Jones, Michael Jefford, Mia Johansson, Anders Johnsson, Therese Juul, Dimitrios Kardamakis, Julia Lai-Kwon, Vicky McFarlane, Isalia MC Miguel, Karen Nugent, Femke Peters, Rachel P Riechelmann, Nazim S Turhal, Shun Wong, Vassilios Vassiliou
International Journal of Radiation Oncology, Biology, Physics
Published: November 16, 2022 https://doi.org/10.1016/j.ijrobp.2022.11.002

Prognostic Impact of Early Treatment and Oxaliplatin Discontinuation in Patients With Stage III Colon Cancer: An ACCENT/IDEA Pooled Analysis of 11 Adjuvant Trials
Claire Gallois, MD; Qian Shi, PhD; Jeffrey P. Meyers, MD; Timothy Iveson, MD; Steven R. Alberts, MD, MPH; Aimery de Gramont , MD; Alberto F. Sobrero, PhD; Daniel G. Haller, MD; Eiji Oki, MD; Anthony Frank Shields, MD, PhD; Richard M. Goldberg, MD; Rachel Kerr, MD; Sara Lonardi , MD; Greg Yothers, PhD; Caroline Kelly, PhD; Ioannis Boukovinas, MD, PhD; Roberto Labianca, MD; Frank A. Sinicrope , MD; Ioannis Souglakos, MD, PhD; Takayuki Yoshino, MD; Jeffrey A. Meyerhardt, MD, MPH; Thierry André, MD, PhD; Demetris Papamichael, MD; and Julien Taieb, MD, PhD;

Development and validation of prognostic models for anal cancer outcomes using distributed learning: protocol for the international multicentre atomCAT2 study
Stelios Theophanous, PerIvar Lonne, Ananya Choudhury, Maaike Berbee, Andre Dekker, Kristopher Dennis, Alice Dewdney, Maria Antonietta Gambacorta, Alexandra Gilbert, Marianne Gronlie Guren, Lois Holloway, Rashmi Jadon, Rohit Kochhar, Ahmed Allam Mohamed, Rebecca Muirhead, Oriol Pares, Lukasz Raszewski, Rajarshi Roy, Andrew Scarsbrook, David SebagMontefiore, Emiliano Spezi, KarenLise Garm Spindler, Baukelien van Triest, Vassilios Vassiliou, Eirik Malinen, Leonard Wee, Ane L. Appelt and on behalf of the atomCAT consortium
Diagnostic and Prognostic Research (2022) 6:14, https://doi.org/10.1186/s41512-022-00128-8


A systematic review of miRNAs as biomarkers for chemotherapyinduced cardiotoxicity in breast cancer patients reveals potentially clinically informative panels as well as key challenges in miRNA research
Cameron Brown, Michael Mantzaris, Elpiniki Nicolaou, Georgia Karanasiou, Elisavet Papageorgiou,Giuseppe Curigliano, Daniela Cardinale, Gerasimos Filippatos, Nikolaos Memos, Katerina K. Naka, Andri Papakostantinou, Paris Vogazianos, Erietta Ioulianou, Christos Shammas, Anastasia Constantinidou, Federica Tozzi, Dimitrios I. Fotiadis and Athos Antoniades
Brown et al. Cardio-Oncology (2022) 8:16, https://doi.org/10.1186/s40959-022-00142-1



Dynamic monitoring of PD-L1 and Ki67 in circulating tumor cells of metastatic non-small cell lung cancer patients treated with pembrolizumab

Maria Spiliotaki, Christiana Michael Neophytou, Paris Vogazianos, Ioannis Stylianou, Gregoria Gregoriou, Andreas Ioannou Constantinou, Constantinos Delta and Haris Charalambous

Molecular Oncology, 2022, doi:10.1002/1878-0261.13317


Clinical Validation of EndoPredict in Pre-Menopausal Women with ER-Positive, HER2-Negative Primary Breast Cancer
Anastasia Constantinidou; Yiola Marcou; Michael S. Toss; Timothy Simmons; Ryan Bernhisel; Elisha Hughes; Braden Probst; Stephanie Meek; Eleni Kakouri; Georgios Georgiou; Ioanna Zouvani; Gabriella Savvidou; Vanessa Kuhl; Jennifer Doedt; Susanne Wagner; Alexander Gutin; Thomas P. Slavin; Jerry S. Lanchbury; Ralf Kronenwett; Ian O. Ellis; Emad A. Rakha;
Clin Cancer Res 2022; Print Issn: 1078-0432; Online Issn: 1557-3265


Efficacy of anti-epidermal growth factor receptor agents in patients with RAS wild-type metastatic colorectal cancer ≥ 70 years
Demetris Papamichael, Guilherme S. Lopes, Curt L. Olswold, Jean-Yves Douillard, Richard A.,Adams, Timothy S. Maughan, Eric Van Cutsem, Alan P. Venook, Heinz-Josef Lenz, Volker Heinemann, Richard Kaplan, Carsten Bokemeyer, Benoist Chibaudel, Axel Grothey, Takayuki Yoshino, John Zalcberg, Aimery De Gramont, Qian Shi
European Journal of Cancer, Volume 163, March 2022, Pages 1-15


Is cancer biology different in older patients? 
Yannick Van Herck, Annelies Feyaerts, Shabbir Alibhai, Demetris Papamichael, Lore Decoster, Yentl Lambrechts, Michael Pinchuk, Oliver Bechter, Jaime Herrera-Caceres, Frédéric Bibeau, Christine Desmedt, Sigrid Hatse, Hans Wildiers
The Lancet Healthy Longevity  Volume 2, Issue 10, October 2021, Pages e663-e677


HRCT appearances in patients with refractory febrile neutropenia in the new anti-mould prophylaxis era
Giannatou E., Cleverley J., Symeonidou C., Prentice A., Kibbler C.
October 2011, Mycoses 54:96-96


Imaging Features of Renal Pathology in the Human Immunodeficiency Virus-Infected Patient
September 2009, Seminars in Ultrasound CT and MRI 30(4):289-97
Chloe Symeonidou, Aysha Hameeduddin


From suspiciously malignant to benign: a pictorial review of FDG PET negative pulmonary lesions on PET/CT and conventional computed tomography
January 2009, Lung Cancer 63(1) Project: Molecular Imaging
Malavika Nathan, Chloe Symeonidou, Sam Stuart, Gemma Wignall


Imaging and Histopathologic Features of HIV-related Renal Disease1
September 2008 Radiographics 28(5):1339-54
Chloe Symeonidou, Richard Standish, Anju Sahdev, Robert D Katz, John F Morlese, Anmol Malhotra


Joint Disease of the Hand: Get a Grip on Your Plain Film Radiology!
November 2007, Conference: Radiological Society of North America
At: Chicago
Rikin Hargunani, Jennifer Williams, Chloe Symeonidou, Jody Maclachlan, Nick Woodward, Brian J Holloway


MRI of Immune-related Neoplasia, Rheumatologic Syndromes, and Other Non-infectious Musculoskeletal Manifestation
November 2007, Conference: Radiological Society of North America
At: Chicago, Project: Body imaging
Thomas C Booth, Chloe Symeonidou, Jody Maclachlan, Tony Jeswani, Brian J Holloway, Mike Anderson


Pneumonia complicating Shigella sonnei dysentery in an HIV-infected adult male
December 2005, International Journal of STD & AIDS 16(11):763-5
DOI:10.1258/095646205774763243 PubMed
Robert F Miller, Chloe Symeonidou, P J Shaw



Inflammatory Sinonasal Disease
November 2005, Conference: Radiological Society of North America 2005 Scientific Assembly and Annual Meeting
Gitta Madani, Chloe Symeonidou, Simon Morley, Valerie J Lund, Timothy Beale


Maltoma: The Forgotten Oma
Conference: Radiological Society of North America 2006 Scientific Assembly and Annual Meeting
John F Morlese, Antony Lawrence, Gough-Palmer, Chloe Symeonidou, Tony Jeswani, Kate Steiner, James Hinton


Imaging and Histopathological Features of HIV Related Nephropathy
Conference: Radiological Society of North America 2006 Scientific Assembly and Annual Meeting
Chloe Symeonidou, John F Morlese, Rikin Hargunani, James Bell, Robert Katz, Anmol Malhotra


Leave No Stone Unturned! Non-Renal Tract Pathology Detected on Low-Dose MDCT KUB
Conference: Radiological Society of North America 2006 Scientific Assembly and Annual Meeting
Rikin Hargunani, James Carmichael, Chloe Symeonidou, John Antony Goode, James Bell, Anmol Malhotra


Short Androgen Suppression and Radiation Dose Escalation in Prostate Cancer: 12-Year Results of EORTC Trial 22991 in Patients With Localized Intermediate-Risk Disease.
Bolla M, Neven A, Maingon P, Carrie C, Boladeras A, Andreopoulos D, Engelen A, Sundar S, van der Steen-Banasik EM, Armstrong J, Peignaux-Casasnovas K, Boustani J, Herrera FG, Pieters BR, Slot A, Bahl A, Scrase CD, Azria D, Jansa J, O'Sullivan JM, Van Den Bergh ACM, Collette L; EORTC Radiation Oncology
J Clin Oncol. 2021 Jul 26:JCO2100855. doi: 10.1200/JCO.21.00855

M. Kohler et al. An international study to revise the EORTC questionnaire for assessing quality of life in lung cancer patients
The Author 2017. Published by Oxford University Press on behalf of the European Society for Medical Oncology.
Gratefully acknowledgement of the contribution of Dr. Nicos Katodritis, Dr. Dimitrios Vomvas, and Loukia Georgiou (Bank of Cyprus Oncology Center, Nicosia) in enrolling patients.

The effect of the use of thyme honey in minimizing radiation-induced oral mucositis in head and neck cancer patients: A randomized controlled trial
Charalambous M, Raftopoulos V, Paikousis L, Katodritis N, Lambrinou E, Vomvas D, Georgiou M, Charalambous A.
Eur J Oncol Nurs. 2018 Jun;34:89-97

P2.17-07 Concurrent Chemoradiotherapy (ConCRT) using Cisplatin-Vinorelbine in Locally Advanced (LA) Non-Small Cell Lung Cancer (NSCLC)
Haris Charalambous, Dimitrios Vomvas, Ifigenia Constantinou, Nicos Katodritis
Journal of Thoracic Oncology 13(10):S854 · October 2018 

Cancer league actions against sunbed use for skin cancer prevention
W.Yared, B.Boonen, G.McElwee, M.Ferguson
Journal of the European Academy of Dermatology and Venerology (JEADV)
First published: 27 February 2019
We are grateful to the following organisations and individuals for contributing to our online surveys from 2012 to 2017: Bank of Cyprus Oncology Centre – N Katodritis; Cancer Focus Northern Ireland – G McElwee, M Ferguson: Cancer Society of Finland – L Laine: Catalan Federation of Entities Against Cancer (FECEC); Cyprus Anti‐Cancer Society – N Katodritis, N Orphanos;

Environmental Assessment of Cytotoxic Drugs in the Oncology Center of Cyprus
Elpidoforos S. Soteriades, Sofia C. Economidou, Artemis Tsivitanidou, Petros Polyviou, Amanda Lorimer, Nikos Katodritis, Stavroula Theophanous-Kitiri
bioRχiv The preprint server for Biology. Posted April 16, 2019

A rare case report of metastatic breast carcinoma in the Oral mucosa and literature review
Hellenic Archives of Oral & Maxillofacial Surgery (2021) 1, 19-26

Reliability and Validity of the Greek Version of the Oral Mucositis Weekly Questionnaire in the Head and Neck Cancer Context
Thrasyvoulou, Stephanie, RN, MSc, Tsitsi, Theologia, RN, PhD, Katodritis Nicos, MD, Vomvas, Dimitrios, MD, Charalambous, Melanie, RN, PhD, Charalambous, Andreas, PhD, RN
Journal of Nursing Measurement, DOI: 10.1891/JNM-D-19-00096 (April 2021)

Synthesis of Recommendations From 25 Countries and 31 Oncology Societies: How to Navigate Through Covid-19 Labyrinth. Kamposioras K, Mauri D, Papadimitriou K, Anthoney A, Hindi N, Petricevic B, Dambrosio M, Valachis A, Kountourakis P, Kopecky J, Kuhar CG, Popovic L, Chilingirova NP, Zarkavelis G, de Mello RA, Plavetić ND, Christopoulos C, Mostert B, Goffin JR, Tzachanis D, Saraireh HH, Ma F, Pavese I, Tolia M.Front Oncol. 2020 Nov 19;10:575148. doi: 10.3389/fonc.2020.575148. eCollection 2020. PMID: 33330049​​

Eur J Surg Oncol
2020 Nov 12;S0748-7983(20)30900-8.
doi: 10.1016/j.ejso.2020.11.007. Online ahead of print.
Outcomes following potentially curative therapies for older patients with metastatic colorectal cancer
Ifigenia Konstantinou 1 , Iestyn M Shapey 2 , Demetris Papamichael 1 , Nicola de Liguori Carino 3

Eur J Surg Oncol
2020 Mar;46(3):363-368.
doi: 10.1016/j.ejso.2020.01.002. Epub 2020 Jan 8.
Adjuvant chemotherapy in patients with colorectal cancer. Is there a role in the older adult?
Demetris Papamichael 1 , Paul Hernandez 2 , Ronak Mistry 3 , Eleni Xenophontos 1 , Chandana Kakani 4

Summary of international recommendations in 23 languages for patients with cancer during the COVID-19 pandemic
Mauri D1,1, Kamposioras K2, Tolia M3, Alongi F4,5, Tzachanis D6; International Oncology Panel and European Cancer Patient Coalition collaborators.
Collaborators (46)
Petricevic B, Chilingirova N, Mihaylova I, Tsakiridis T, Salembier C, Papadimitriou K, De Mello RA, Amaral GA, Neves NM, Dias R, Yi J, Dedic Plavetic N, Antunac K, Kountourakis P, Kopecky J, Christopoulos C, Pavese I, Corradini S, Zarkavelis G, Papadaki A, Gkantaifi A, Theodorelos V, Capizzello A, Lovey J, Cellini F, Dambrosio M, Takeuchi D, Saraireh HH, Røtterud R, Chojnacka M, Papachristos A, Djan I, Popovic L, Grašič Kuhar C, Strojan P, Hindi N, Valachis A, Åhs M, De Bari B, Santa Cruz O, Hameed H, Takeuchi E, Apostolidis K, Cardone A, Gono P, Filis P.
Lancet Oncol. 2020 May 13. doi: 10.1016/S1470-2045(20)30278-3

Patient and family support in the era of fake e-medicine: food for thought from an international consensus panel.
Mauri D, Kamposioras K, Tzachanis D, Tolia M, Valachis A, Dambrosio M, Alongi F, De Mello RA, Lövey J, Anthoney A, Christopoulos C, Saraireh HH, Kountourakis P, Kampletsas E, Tsali L, Tsakiridis T, Kosovitsas I, Soukovelos A, Lymperatou D, Polyzos N, Zarkavelis G.
ESMO Open. 2020 Apr;5(2). pii: e000696. doi: 10.1136/esmoopen-2020-000696.

Consensus statement of the Hellenic and Cypriot Gastric Cancer Study Group on the diagnosis, staging and management of gastric cancer
Douridas GN, Fountoulakis A, Souglakos J, Gourtsoyianni S, Vini L, Levidou G, Liakakos T, Agalianos C, Dervenis C, Kalogeridi MA, Karavokyros I, Koumarianou A, Kountourakis P, Oikonomopoulos G, Economopoulou P, Sgouros J, Sgouros SN, Stamou K, Triantopoulou C, Zacharoulis D, Gouvas N, Xynos E.
Updates Surg. 2020 Feb 28. doi: 10.1007/s13304-020-00723-8. [Epub ahead of print]
PMID: 32112342​

Adjuvant chemotherapy in patients with colorectal cancer. Is there a role in the older adult?
Papamichael D1, Hernandez P2, Mistry R3, Xenophontos E1, Kakani C4.
Eur J Surg Oncol. 2020 Jan 8. pii: S0748-7983(20)30002-0. doi: 10.1016/j.ejso.2020.01.002. [Epub ahead of print]

Recommended ESTRO Core Curriculum for Radiation Oncology/Radiotherapy 4th edition.
Benstead K, Lara PC, Andreopoulos D, Bibault JE, Dix A, Eller YG, Franco P, Guiliani M, Jaal J, Juretic A, Kozma E, Lumsden G, Maddalo M, Magrini S, Mjaaland I, Pfeffer R, de Sousa de Sa Pinto OMT, Spalek M, Vozenin MC, Verfaillie C, Van Egten V, Eriksen JG.
Radiother Oncol. 2019 Dec;141:1-4. doi: 10.1016/j.radonc.2019.08.013. Epub 2019 Sep 5.

Consensus statement of the Hellenic and Cypriot Oesophageal Cancer Study Group on the diagnosis, staging and management of oesophageal cancer.
Fountoulakis A, Souglakos J, Vini L, Douridas GN, Koumarianou A, Kountourakis P, Agalianos C, Alexandrou A, Dervenis C, Gourtsoyianni S, Gouvas N, Kalogeridi MA, Levidou G, Liakakos T, Sgouros J, Sgouros SN, Triantopoulou C, Xynos E.
Updates Surg. 2019 Dec 2.

Personalized management of elderly patients with rectal cancer: Expert recommendations of the European Society of Surgical Oncology, European Society of Coloproctology, International Society of Geriatric Oncology, and American College of Surgeons Commission on Cancer.
Montroni I, Ugolini G, Saur NM, Spinelli A, Rostoft S, Millan M, Wolthuis A, Daniels IR, Hompes R, Penna M, Fürst A, Papamichael D, Desai AM, Cascinu S, Gèrard JP, Myint AS, Lemmens VEPP, Berho M, Lawler M, De Liguori Carino N, Potenti F, Nanni O, Altini M, Beets G, Rutten H, Winchester D, Wexner SD, Audisio RA.
Eur J Surg Oncol. 2018 Aug 15. pii: S0748-7983(18)31272-1. doi: 10.1016/j.ejso.2018.08.003. [Epub ahead of print] Review. PMID: 30150158

Optimal management of localized rectal cancer in older patients.
Bujko K, Glynne-Jones R, Papamichael D, Rutten HJT.
J Geriatr Oncol. 2018 Aug 24. pii: S1879-4068(18)30225-X. doi: 10.1016/j.jgo.2018.08.001. [Epub ahead of print] PMID: 30150020

Advances in molecular, genetic and immune signatures of gastric cancer: Are we ready to apply them in our patients' decision making?
Gkolfinopoulos S, Papamichael D, Papadimitriou K, Papanastasopoulos P, Vassiliou V, Kountourakis P.
World J Gastrointest Oncol. 2018 Jul 15;10(7):172-183. doi: 10.4251/wjgo.v10.i7.172. Review

Identifying patients who may benefit from oxaliplatin-containing perioperative chemo(radio)therapy for rectal cancer
D PapamichaelR Glynne-Jones 
Annals of Oncology, Volume 29, Issue 8, 1 August 2018, Pages 1616–1618

Fournier Gangrene in a patient receiving chemo–radiation for rectal cancer
Maria Pittaka1, Chrysanthos Georgiou2, Petros Polyviou3, Pantelis Kountourakis4, Panayiotis Loizou2, Ifigenia Constantinou4, Demetris Andreopoulos1 and Vassilios P Vassiliou1,*
1 Department of Radiation Oncology, Bank of Cyprus Oncology Center, Nicosia, Cyprus, 2 Department of General Surgery, Nicosia General Hospital, Nicosia, Cyprus, 3 Diagnostic Radiology, Bank of Cyprus Oncology Center, Nicosia, Cyprus, and 4 Department of Medical Oncology, Bank of Cyprus Oncology Center, Nicosia, Cyprus


Leptomeningeal metastases originated from esophagogastric junction/gastric cancer: A brief report of two cases.
Kountourakis P, Papamichael D, Haralambous H, Michael M, Nakos G, Lazaridou S, Fotiou E, Vassiliou V, Andreopoulos D.
World J Gastrointest Oncol. 2018 Jan 15;10(1):56-61. doi: 10.4251/wjgo.v10.i1.56.
PMID: 29375749

Observed benefit and safety of aflibercept in elderly patients with metastatic colorectal cancer: An age-based analysis from the randomized placebo-controlled phase III VELOUR trial.
Ruff P, Van Cutsem E, Lakomy R, Prausova J, van Hazel GA, Moiseyenko VM, Soussan-Lazard K, Dochy E, Magherini E, Macarulla T, Papamichael D.
J Geriatr Oncol. 2017 Aug 12. pii: S1879-4068(17)30140-6. doi: 10.1016/j.jgo.2017.07.010. [Epub ahead of print]

Management of gastric cancer in older adults.
Matthaiou C, Papamichael D.
J Geriatr Oncol. 2017 Aug 1. pii: S1879-4068(17)30136-4. doi: 10.1016/j.jgo.2017.07.009. [Epub ahead of print]

Chromogranin A as a valid marker in oncology: Clinical application or false hopes?
Gkolfinopoulos S, Tsapakidis K, Papadimitriou K, Papamichael D, Kountourakis P.
World J Methodol. 2017 Mar 26;7(1):9-15. doi: 10.5662/wjm.v7.i1.9. eCollection 2017 Mar 26. Review.
PMID: 28396845

Geriatric factors and outcomes in metastatic colorectal cancer
European Journal of Cancer, DOI: http://dx.doi.org/10.1016/j.ejca.2016.11.003
Demetris Papamichael, Matti Aapro

The effectiveness of thyme honey for the management of treatment-induced xerostomia in head and neck cancer patients: A feasibility randomized control trial
Andreas Charalambous, Ekaterini Lambrinou, Nicos Katodritis, Dimitrios Vomvas, Vasilios Raftopoulos, Morpho Georgiou, Lefkios Paikousis, Melanie Charalambous
European Journal of Oncology Nursing 27 (2017) 1-8

BRCA1 and BRCA2 mutation testing in Cyprus; a population based study.
Loizidou MA, Hadjisavvas A, Pirpa P, Spanou E, Delikurt T, Tanteles GA, Daniel M, Kountourakis P, Malas S, Ioannidis G, Zouvani I, Kakouri E, Papamichael D, Marcou Y, Anastasiadou V, Kyriacou K.
Clin Genet. 2016 Oct 13. doi: 10.1111/cge.12886. [Epub ahead of print]

Randomised, open-label, phase II study of gemcitabine with and without IMM-101 for advanced pancreatic cancer.
Dalgleish AG, Stebbing J, Adamson DJ, Arif SS, Bidoli P, Chang D, Cheeseman S, Diaz-Beveridge R, Fernandez-Martos C, Glynne-Jones R, Granetto C, Massuti B, McAdam K, McDermott R, Martín AJ, Papamichael D, Pazo-Cid R, Vieitez JM, Zaniboni A, Carroll KJ, Wagle S, Gaya A, Mudan SS.
Br J Cancer. 2016 Oct 11. doi: 10.1038/bjc.2016.342

Clinical practice guidelines for the management of metastatic colorectal cancer: a consensus statement of the Hellenic Society of Medical Oncologists (HeSMO).
Dervenis C, Xynos E, Sotiropoulos G, Gouvas N, Boukovinas I, Agalianos C, Androulakis N, Athanasiadis A, Christodoulou C, Chrysou E, Emmanouilidis C, Georgiou P, Karachaliou N, Katopodi O, Kountourakis P, Kyriazanos I, Makatsoris T, Papakostas P, Papamichael D, Pechlivanides G, Pentheroudakis G, Pilpilidis I, Sgouros J, Tekkis P, Triantopoulou C, Tzardi M, Vassiliou V, Vini L, Xynogalos S, Ziras N, Souglakos J.
Ann Gastroenterol. 2016 Oct-Dec;29(4):390-416.


Follicle-Stimulating Hormone Receptor (FSHR): A Promising Tool in Oncology?
Papadimitriou K, Kountourakis P, Kottorou AE, Antonacopoulou AG, Rolfo C, Peeters M, Kalofonos HP.
Mol Diagn Ther. 2016 Jul 8. [Epub ahead of print] Review.

Validity of Adjuvant! Online in older patients with stage III colon cancer based on 2967 patients from the ACCENT database.
Papamichael D, Renfro LA, Matthaiou C, Yothers G, Saltz L, Guthrie KA, Van Cutsem E, Schmoll HJ, Labianca R, André T, O'Connell M, Alberts SR, Haller DG, Kountourakis P, Sargent DJ; Adjuvant Colon Cancer Endpoints (ACCENT) Group.
J Geriatr Oncol. 2016 Jul 25. pii: S1879-4068(16)30088-1. doi: 10.1016/j.jgo.2016.07.002. [Epub ahead of print] PMID:27468630

Guided Imagery And Progressive Muscle Relaxation as a Cluster of Symptoms Management Intervention in Patients Receiving Chemotherapy: A Randomized Control Trial.

Charalambous A1,2, Giannakopoulou M3, Bozas E3, Marcou Y4, Kitsios P4, Paikousis L5.

PLoS One. 2016 Jun 24;11(6):e0156911. doi: 10.1371/journal.pone.0156911. eCollection 2016.

ESMO consensus guidelines for the management of patients with metastatic colorectal cancer.
Van Cutsem E, Cervantes A, Adam R, Sobrero A, Van Krieken JH, Aderka D, Aranda Aguilar E, Bardelli A, Benson A, Bodoky G, Ciardiello F, D'Hoore A, Diaz-Rubio E, Douillard JY, Ducreux M, Falcone A, Grothey A, Gruenberger T, Haustermans K, Heinemann V, Hoff P, Köhne CH, Labianca R, Laurent-Puig P, Ma B, Maughan T, Muro K, Normanno N, Österlund P, Oyen WJ, Papamichael D, Pentheroudakis G, Pfeiffer P, Price TJ, Punt C, Ricke J, Roth A, Salazar R, Scheithauer W, Schmoll HJ, Tabernero J, Taïeb J, Tejpar S, Wasan H, Yoshino T, Zaanan A, Arnold D.
Ann Oncol. 2016 Aug;27(8):1386-422. doi: 10.1093/annonc/mdw235. Epub 2016 Jul 5.

Short Androgen Suppression and Radiation Dose Escalation for Intermediate- and High-Risk Localized Prostate Cancer: Results of EORTC Trial 22991.

Bolla M, Maingon P, Carrie C, Villa S, Kitsios P, Poortmans PM, Sundar S, van der Steen-Banasik EM, Armstrong J, Bosset JF, Herrera FG, Pieters B, Slot A, Bahl A, Ben-Yosef R, Boehmer D, Scrase C, Renard L, Shash E, Coens C, van den Bergh AC, Collette L.

J Clin Oncol. 2016 May 20;34(15):1748-56. doi: 10.1200/JCO.2015.64.8055. Epub 2016 Mar 14.

Clinical practice guidelines for the surgical management of colon cancer: a consensus statement of the Hellenic and Cypriot Colorectal Cancer Study Group by the HeSMO.
Xynos E, Gouvas N, Triantopoulou C, Tekkis P, Vini L, Tzardi M, Boukovinas I, Androulakis N, Athanasiadis A, Christodoulou C, Chrysou E, Dervenis C, Emmanouilidis C, Georgiou P, Katopodi O, Kountourakis P, Makatsoris T, Papakostas P, Papamichael D, Pentheroudakis G, Pilpilidis I, Sgouros J, Vassiliou V, Xynogalos S, Ziras N, Karachaliou N, Zoras O, Agalianos C, Souglakos J; [the Executive Team on behalf of the Hellenic Society of Medical Oncology (HeSMO)].
Ann Gastroenterol. 2016 Jan-Mar;29(1):3-17.

The ALPPS procedure as a novel "liver-first" approach in treating liver metastases of colon cancer: the first experience in Greek Cypriot area.
Petrou A, Moris D, Kountourakis P, Fard-Aghaie M, Neofytou K, Felekouras E, Papalampros A.
World J Surg Oncol. 2016 Mar 8;14(1):67. doi: 10.1186/s12957-016-0827-3.

Clinical practice guidelines for the surgical treatment of rectal cancer: a consensus statement of the Hellenic Society of Medical Oncologists (HeSMO).
Xynos E, Tekkis P, Gouvas N, Vini L, Chrysou E, Tzardi M, Vassiliou V, Boukovinas I, Agalianos C, Androulakis N, Athanasiadis A,
Christodoulou C, Dervenis C, Emmanouilidis C, Georgiou P, Katopodi O, Kountourakis P, Makatsoris T, Papakostas P, Papamichael D,
Pechlivanides G, Pentheroudakis G, Pilpilidis I, Sgouros J, Triantopoulou C, Xynogalos S, Karachaliou N, Ziras N, Zoras O, Souglakos J;
[the Executive Team on behalf of the Hellenic Society of Medical Oncologists (HeSMO)].
Ann Gastroenterol. 2016 Apr-Jun;29(2):103-26. doi: 10.20524/aog.2016.0003.

Adjuvant chemotherapy for colon cancer: a consensus statement of the Hellenic and Cypriot Colorectal Cancer Study Group by the HeSMO.
Kountourakis P, Souglakos J, Gouvas N, Androulakis N, Athanasiadis A, Boukovinas I, Christodoulou C, Chrysou E, Dervenis C, Emmanouilidis C, Georgiou P, Karachaliou N, Katopodi O, Makatsoris T, Papakostas P, Pentheroudakis G, Pilpilidis I, Sgouros J, Tekkis P, Triantopoulou C, Tzardi M, Vassiliou V, Vini L, Xynogalos S, Xynos E, Ziras N, Papamichael D.
Ann Gastroenterol. 2016 Jan-Mar;29(1):18-23.PMID:26751386 Free PMC Article

Adjuvant Fluorouracil, Leucovorin, and Oxaliplatin in Stage II to III Colon Cancer: Updated 10-Year Survival and Outcomes According to BRAF Mutation and Mismatch Repair Status of the MOSAIC Study
Thierry André, Armand de Gramont, Dewi Vernerey, Benoist Chibaudel, Franck Bonnetain, Annemilaï Tijeras-Raballand, Aurelie Scriva, Tamas Hickish, Josep Tabernero, Jean Luc Van Laethem, Maria Banzi, Eduard Maartense, Einat Shmueli, Goran U. Carlsson, Werner Scheithauer, Demetris Papamichael, Marcus Möehler, Stefania Landolfi, Pieter Demetter, Soudhir Colote, Christophe Tournigand, Christophe Louvet, Alex Duval, Jean-François Fléjou and Aimery de Gramont
Journal of Clinical Oncology, JCO published online on November 2, 2015; DOI:10.1200/JCO.2015.63.4238

Oral single-agent chemotherapy in older patients with solid tumours: A position paper from the International Society of Geriatric Oncology (SIOG).
Biganzoli L, Lichtman S, Michel JP, Papamichael D, Quoix E, Walko C, Aapro M.
Eur J Cancer. 2015 Sep 1. pii: S0959-8049(15)00780-7. doi: 10.1016/j.ejca.2015.08.005. [Epub ahead of print] Review.

Difficulties in deciding whether to ablate patients with putatively "low-intermediate-risk" differentiated thyroid carcinoma: do guidelines mainly apply in the centres that produce them? Results of a retrospective, two-centre quality assurance study.
Frangos S, Iakovou IP, Marlowe RJ, Eftychiou N, Patsali L, Vanezi A, Savva A, Mpalaris V, Giannoula EI.
Eur J Nucl Med Mol Imaging. 2015 Aug 1. [Epub ahead of print]

A study of gene expression markers for predictive significance for bevacizumab benefit in patients with metastatic colon cancer: a translational research study of the Hellenic Cooperative Oncology Group (HeCOG).
Pentheroudakis G, Kotoula V, Fountzilas E, Kouvatseas G, Basdanis G, Xanthakis I, Makatsoris T, Charalambous E, Papamichael D, Samantas E, Papakostas P, Bafaloukos D, Razis E, Christodoulou C, Varthalitis I, Pavlidis N, Fountzilas G. BMC Cancer. 2014 Feb 20;14:111. doi: 10.1186/1471-2407-14-111

The mutational spectrum of Lynch syndrome in cyprus.
Loizidou MA, Neophytou I, Papamichael D, Kountourakis P, Vassiliou V, Marcou Y, Kakouri E, Ioannidis G, Philippou C, Spanou E, Tanteles GA, Anastasiadou V, Hadjisavvas A, Kyriacou K.
PLoS One. 2014 Aug 18;9(8):e105501. doi: 10.1371/journal.pone.0105501. eCollection 2014. PMID: 25133505

Adjuvant Chemoradiation Therapy in Gastric Cancer: Critically Reviewing the Past and Visualizing the Next Step Forward.
Papadimitriou K, Antoniou G, Rolfo C, Russo A, Bronte G, Vassiliou V, Papamichael D, Peeters M, Kountourakis P.
Gastroenterol Res Pract. 2015;2015:650846. doi: 10.1155/2015/650846. Epub 2015 May 26. Review. PMID: 26101524

Melanoma of the gallbladder: appropriate surgical management and review of the literature.
Demetris Christou, Nicos Katodritis, Marios P. Decatris, Angela Katodritou, Ioannis Michaelides, Nicolaos Nicolaou, Michalis Kounoushis and Panayiotis Hadjicostas
Clinical Case Reports 2014;2(4)

Voice disorders induced by bevacizumab administration in an ovarian cancer patient: An underestimated and rare toxicity.

Kountourakis P, Antoniou G, Papadimitriou K, Vassiliou V, Syrigos D, Philippou M,

Hematol Oncol Stem Cell Ther. 2014 Jul 25. pii: S1658-3876(14)00050-8. doi: 10.1016/j.hemonc.2014.06.003. [Epub ahead of print]

Treatment of colorectal cancer in older patients. International Society of Geriatric Oncology (SIOG) consensus recommendations 2013.

Papamichael D, Audisio RA, Glimelius B, de Gramont A, Glynne-Jones R, Haller D, Köhne CH, Rostoft S, Lemmens V, Mitry E, Rutten H, Sargent D, Sastre J, Seymour M, Starling N, Van Cutsem E, Aapro M.

Ann Oncol. 2014 Jul 11. pii: mdu253. [Epub ahead of print]


FCGR polymorphisms and cetuximab efficacy in chemorefractory metastatic colorectal cancer: an international consortium study.

Geva R, Vecchione L, Kalogeras KT, Vittrup Jensen B, Lenz HJ, Yoshino T, Paez D, Montagut C, Souglakos J, Cappuzzo F, Cervantes A, Frattini M, Fountzilas G, Johansen JS, Høgdall EV, Zhang W, Yang D, Yamazaki K, Nishina T, Papamichael D, Vincenzi B, Macarulla T, Loupakis F, De Schutter J, Spindler KL, Pfeiffer P, Ciardiello F, Piessevaux H, Tejpar S.

Gut. 2014 Jul 10. pii: gutjnl-2014-307234. doi: 10.1136/gutjnl-2014-307234. [Epub ahead of print]

Treatment of older patients with colorectal cancer: a perspective review.

Kordatou Z, Kountourakis P, Papamichael D.

Ther Adv Med Oncol. 2014 May;6(3):128-40. doi: 10.1177/1758834014523328. Review.


EGFR gene gain and PTEN protein expression are favorable prognostic factors in patients with KRAS wild-type metastatic colorectal cancer treated with cetuximab.

Razis E, Pentheroudakis G, Rigakos G, Bobos M, Kouvatseas G, Tzaida O, Makatsoris T, Papakostas P, Bai M, Goussia A, Samantas E, Papamichael D, Romanidou O, Efstratiou I, Tsolaki E, Psyrri A, De Roock W, Bafaloukos D, Klouvas G, Tejpar S, Kalogeras KT, Pectasides D, Fountzilas G.

J Cancer Res Clin Oncol. 2014 May;140(5):737-48. doi: 10.1007/s00432-014-1626-2. Epub 2014 Mar 5.

Adjuvant therapy for resectable pancreatic adenocarcinoma: Review of the current treatment approaches and future directions.
Antoniou G, Kountourakis P, Papadimitriou K, Vassiliou V, Papamichael D.
Cancer Treat Rev. 2014 Feb;40(1):78-85. doi: 10.1016/j.ctrv.2013.05.008. Epub 2013 Jun 26.

The prognostic role of ephrin A2 and endothelial growth factor receptor pathway mediators in patients with advanced colorectal cancer treated with cetuximab.
Strimpakos A, Pentheroudakis G, Kotoula V, De Roock W, Kouvatseas G, Papakostas P, Makatsoris T, Papamichael D, Andreadou A, Sgouros J, Zizi-Sermpetzoglou A, Kominea A, Televantou D, Razis E, Galani E, Pectasides D, Tejpar S, Syrigos K, Fountzilas G.
Clin Colorectal Cancer. 2013 Dec;12(4):267-274.e2. doi: 10.1016/j.clcc.2013.07.001. Epub 2013 Sep 17.

Radiotherapy capacity in Europe
Charalambous H, Marcou Y, Katodritis N, Kountourakis P, Andreopoulos D.
Lancet Oncol. 2013 May;14(6):e196

Biomarkers of benefit from cetuximab-based therapy in metastatic colorectal cancer: interaction of EGFR ligand expression with RAS/RAF, PIK3CA genotypes.
Pentheroudakis G, Kotoula V, De Roock W, Kouvatseas G, Papakostas P, Makatsoris T, Papamichael D, Xanthakis I, Sgouros J, Televantou D, Kafiri G, Tsamandas AC, Razis E, Galani E, Bafaloukos D, Efstratiou I, Bompolaki I, Pectasides D, Pavlidis N, Tejpar S, Fountzilas G.
BMC Cancer. 2013 Feb 2;13(1):49. [Epub ahead of print]

Expression profiling of 21 biomolecules in locally advanced nasopharyngeal carcinomas of Caucasian patients.
Krikelis D, Bobos M, Karayannopoulou G, Resiga L, Chrysafi S, Samantas E, Andreopoulos D, Vasiliou V, Ciuleanu E, Fountzilas G.
BMC Clin Pathol. 2013 Jan 29;13:1

The role of radiotherapy (RT) in the management of metastatic bone disease
Vassiliou V, Kountourakis P, Kardamakis D
(FCO 2012;3:35-40)

The role of radiotherapy (RT) for the management of painful bone metastases.
Vassiliou V, Vomvas D, Kountourakis P, Polyviou P, Andreopoulos D
(Journal of Pain Management 2012;5:4)

Pharmacologic management of uncomplicated painful bone metastases
Vomvas D, Kountourakis P, Polyviou P, Andreopoulos D, Vassiliou V
(Journal of Pain Management 2012;5:4)

Low-grade cribriform cystadenocarcinoma of the parotid gland
Dimitrios Vomvas, Stavros Kallis, Petros Polyviou, Haris Charalambous, Nicos Katodritis
Forum of Clinical Oncology, Vol 3, No 4 (2012)

Treatment of colorectal cancer in older patients.
Audisio RA, Papamichael D.
Nat Rev Gastroenterol Hepatol. 2012 Dec;9(12):716-25. doi: 10.1038/nrgastro.2012.196. Epub 2012 Oct 9
Adjuvant chemoradiotherapy (CRT) for high-risk gastric cancer (GC) patients: single-center experience using infusional 5-fluorouracil (5FU) and radiotherapy (RT).
Papadimitriou K, Vassiliou V, Kountourakis P, Polyviou P, Andreopoulos D, Papamichael D.
Med Oncol. 2012 Dec;29(4):2716-7. doi: 10.1007/s12032-012-0206-z. Epub 2012 Mar 15.
ESMO Consensus Guidelines for management of patients with colon and rectal cancer. a personalized approach to clinical decision making.
Schmoll HJ, Van Cutsem E, Stein A, Valentini V, Glimelius B, Haustermans K, Nordlinger B, van de Velde CJ, Balmana J, Regula J, Nagtegaal ID, Beets-Tan RG, Arnold D, Ciardiello F, Hoff P, Kerr D, Köhne CH, Labianca R, Price T, Scheithauer W, Sobrero A, Tabernero J, Aderka D, Barroso S, Bodoky G, Douillard JY, El Ghazaly H, Gallardo J, Garin A, Glynne-Jones R, Jordan K, Meshcheryakov A, Papamichail D, Pfeiffer P, Souglakos I, Turhal S, Cervantes A.
Ann Oncol. 2012 Oct;23(10):2479-516.

Chemo re-irradiation in recurrent head and neck cancer: a single institution experience.
N. Katodritis, H. Charalampous, D. Vomvas.
J BUON Vol. 17, No 2, 2012, pp 397

Assessment of sexual function in patients with cancer undergoing radiotherapy - a single centre prospective study.
Vomvas D, Iconomou G, Soubasi E, Leotsinidis M, Kalofonos HP, Beratis S, Kardamakis D, Assimakopoulos K.
Anticancer Res. 2012 Feb;32(2):657-64.

Mesothelioma in Cyprus: a case series (1997-2007).
Orphanos G, Charalambous C, Vrezas I, Kales SN, Haralambous H, Katodritis N, Christodoulides G, Maimaris M, Soteriades ES.
Hematol Oncol Stem Cell Ther. 2011;4(4):193-4. PMID: 22198194 [PubMed - in process]

Abolished circadian rhythm of salivary cortisol in elite artistic gymnasts
Neoklis A. Georgopoulos, Loredana Rottstein, Athanasios Tsekouras, Anastasia heodoropoulou, Eftychia Koukkou, Panagiotis Mylonas, George Polykarpou, Evgenia Lampropoulou, Gregoris Iconomou, Michel Leglise, Apostolos G. Vagenakis, Kostas B. Markou
Steroids Volume 76, Issue 4, March 2011, Pages 353–357

Targeted agents: review of toxicity in the elderly metastatic colorectal cancer patients.
Papamichael D, Kyriakou F, Kountourakis P
Target Oncol. 2011 Nov 9. [Epub ahead of print]

Barrett’s esophagus: treatment or observation of a major precursor factor of esophageal cancer?
P. Kountourakis, K. Papademetriou, A. Ardavanis, D. Papamichael
J BUON 16: 425-430, 2011

Isolated right atrial metastasis of malignant melanoma mimicking a myxoma.
Kontozis L, Soteriou M, Papamichael D, Economides C, Bagdades E, Christou C, Oxynou C.
Hellenic J Cardiol. 2011 May-Jun;52(3):281-4

Bone metastases: assessment of therapeutic response through radiological and nuclear medicine imaging modalities.
Vassiliou Vassilios, Andreopoulos Dimitrios, Frangos Savvas, Tselis Nicolaos, Giannopoulou Efstathia, Lutz Stephen.
Clinical Oncology Journal. Accepted for publication

Visual and hearing loss due to colorectal meningeal carcinomatosis: a case-based review
Kountourakis P, Ardavanis A.
Clin Adv Hematol Oncol. 2010 Aug;8(8):567-8. Review. No abstract available. PMID: 20966894 [PubMed - indexed for MEDLINE]Related citations

Combined modality therapy of cT2N0M0 esophageal cancer: the University of Texas M. D. Anderson Cancer Center experience
Kountourakis P, Correa AM, Hofstetter WL, Lee JH, Bhutani MS, Rice DC, Komaki R, Maru DM, Ross WA, Vaporciyan A, Swisher SG, Ajani JA.
Cancer. 2010 Oct 19. [Epub ahead of print]PMID: 20960497 [PubMed - as supplied by publisher]Related citations

A phase I trial of adoptive transfer of allogeneic natural killer cells in patients with advanced non-small cell lung cancer
Iliopoulou EG, Kountourakis P, Karamouzis MV, Doufexis D, Ardavanis A, Baxevanis CN, Rigatos G, Papamichail M, Perez SA.
Cancer Immunol Immunother. 2010 Dec;59(12):1781-9. Epub 2010 Aug 12.PMID: 20703455 [PubMed - indexed for MEDLINE]Related citations

Bevacizumab combined with two-weekly paclitaxel as first-line therapy for metastatic breast cancer
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Irinotecan/fluorouracil/leucovorin or the same regimen followed by oxaliplatin/fluorouracil/leucovorin in metastatic colorectal cancer.
Kalofonos HP, Papakostas P, Makatsoris T, Papamichael D, Vourli G, Xanthakis I, Aravantinos G, Papadimitriou C, Pentheroudakis G, Varthalitis I, Samelis G, Syrigos KN, Xiros N, Stavropoulos M, Kosmidis P, Christodoulou C, Linardou H, Skondra M, Pectasides D, Economopoulos T, Fountzilas G.
Anticancer Res. 2010 Oct;30(10):4325-33.

Intramedullary Spinal Cord Metastasis in a Patient with Colon Cancer: A Case Report.
Vassiliou V, Papamichael D, Polyviou P, Koukouma A, Andreopoulos D.
J Gastrointest Cancer. 2010 Sep 14. [Epub ahead of print]PMID: 20838936 [PubMed - as supplied by publisher]

Effects of KRAS, BRAF, NRAS and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective population-based Consortium analysis.
De Roock W, Claes B, Bernasconi D, De Schutter J, Biesmans B, Fountzilas G, Kalogeras KT, Kotoula V, Papamichael D, Laurent-Puig P, Penault-Llorca F, Rougier P, Vincenzi B, Santini D, Tonini G, Cappuzzo F, Frattini M, Molinari F, Saletti P, De Dosso S, Martini M, Bardelli A, Siena S, Sartore-Bianchi A, Tabernero J, Macarulla T, Di Fiore F, Gangloff AO, Ciardiello F, Pfeiffer P, Qvortrup C, Hansen TP, Van Cutsem E, Piessevaux H, Lambrechts D, Delorenzi M, Tejpar S. 
Lancet Oncol. 2010 Jul 7. [Epub ahead of print]

Cetuximab plus FOLFOX6 or FOLFIRI in metastatic colorectal cancer: CECOG trial.
Ocvirk J, Brodowicz T, Wrba F, Ciuleanu TE, Kurteva G, Beslija S, Koza I, Pápai Z, Messinger D, Yilmaz U, Faluhelyi Z, Yalcin S, Papamichael D, Wenczl M, Mrsic-Krmpotic Z, Shacham-Shmueli E, Vrbanec D, Esser R, Scheithauer W, Zielinski CC. 
World J Gastroenterol. 2010 Jul 7;16(25):3133-43

Assessment of therapeutic response in patients with metastatic skeletal disease: suggested modifications for the MDA response classification criteria.
Vassiliou V, Andreopoulos D.
Br J Cancer. 2010 Jul 27. PMID: 20664592

Hyperthermic isolated limb perfusion for recurrent melanomas and soft tissue sarcomas: feasibility and reproducibility in a multi-institutional Hellenic collaborative study.
Lasithiotakis K, Economou G, Gogas H, Ioannou C, Perisynakis K, Filis D, Kastana O, Bafaloukos D, Decatris M, Catodritis N, Frangia K, Papadakis G, Magarakis M, Tsoutsos D, Chrysos E, Chalkiadakis G, Zoras O.
Oncol Rep. 2010 Apr;23(4):1077-83.
PMID: 20204294 [PubMed - indexed for MEDLINE

Osteonecrosis of the jaws: Clinico-pathlogical and radiologic characteristics, prevalence and treatment strategies.
Vassiliou V, Tselis N, Kardamakis D.
Strahlenther Onkol. 2010 Jul;186(7):367-73. Epub 2010 Apr 26. Review.

EORTC Elderly Task Force experts’ opinion for the treatment of colon cancer in older patients.
A.G. Pallis , D. Papamichael , R. Audisio , M. Peeters , G. Folprecht , D. Lacombe , E. Van Cutsem.
Cancer Treat Rev. 2010 Feb;36(1):83-90

Implications of k-ras mutation status for the treatment of metastatic colorectal cancer.
Fortunato Ciardiello, Sabine Tejpar, Demetris Papamichael. 
Target Oncol. 2009 Dec;4(4):311-22

Expression and prognostic significance of kallikrein-related peptidase 8 protein levels in advanced ovarian cancer by using automated quantitative analysis.
Kountourakis P, Psyrri A, Scorilas A, Markakis S, Kowalski D, Camp RL, Diamandis EP, Dimopoulos MA.
Thromb Haemost. 2009 Mar;101(3):541-6.

The potential role of Bcl-2 and Ki67 expression and apoptosis in gastric carcinoma. A clinicopatholoic study.
Tsamandas AC, Kardamakis D, Tsiamalos P, Liava A, Tzelepi V, Vassiliou V, Petsas T,. Scopa CD, Vagenas K.
Anticancer Research, 2009;29:703-709

Management of symptomatic bone metastases from breast cancer with concomitant use of external radiotherapy and ibandronate: results of a prospective, pilot study.
Vassiliou V, Kalogeropoulou C, Leotsinidis M, Tsamandas A, Petsas T, Giannopoulou E, Kardamakis D.
The Breast Journal, 2009(1):92-94

The management of metastatic bone disease with the combination of bisphosphonates and radiotherapy: From theory to clinical practice.
Vassiliou Vassilios, Kardamakis Dimitrios.
Anticancer Agents in Medicinal Chemistry, 2009;9(3):326-335.

The role of postoperative radiotherapy in patients with thymic tumors – a retrospective study and review of the literature
Vassiliou Vassilios, Tsamandas Athanassios, Katodritis Nicos, Charoulis Nikolaos, Koukouma Alona, Andreopoulos Dimitrios, Salakou Stavroula,   Zolota Vassiliki, Papathanassopoulos Panagiotis, Christodoulides Gregoris,Dougenis Dimitrios, Kardamakis Dimitrios.
Journal In VIVO, 2009;23:843-852

Concurrent application of bisphosphonates and external beam radiotherapy in patients with metastatic bone disease from renal cancer.
Vassiliou Vassilios, Leotsinides Michael, Kalogeropoulou Christina,Kardamakis Dimitrios.
British Journal of Urology International 2009;104:417-418

Combining systemic Bisphosphonates with palliative external beam radiotherapy or bone targeted Radionuclide therapy: interactions and effectiveness.
Vassiliou V, Bruland O, Janjan N, Lutz S, Kardamakis D, Hoskin P.
Clinical Oncology, 2009;21:665-667

Kardamakis D, Vassiliou V, Chow E, eds. 
Book title: “Bone Metastases: A Translational and Clinical Approach”. Springer, 2009, ISBN: 978-1-4020-9818-5.

Acute toxicity of curative radiotherapy for intermediate- and high-risk localised prostate cancer in the EORTC trial 22991.

Randomized controlled trial
Matzinger O1, Duclos F, van den Bergh A, Carrie C, Villà S, Kitsios P, Poortmans P, Sundar S, van der Steen-Banasik EM, Gulyban A, Collette L, Bolla M; EORTC Radiation Oncology Group.

Eur J Cancer. 2009 Nov;45(16):2825-34. doi: 10.1016/j.ejca.2009.07.009. Epub 2009 Aug 12

EORTC Elderly Task Force experts' opinion for the treatment of colon cancer in older patients.
Pallis AG, Papamichael D, Audisio R, Peeters M, Folprecht G, Lacombe D, Van Cutsem E.
Cancer Treat Rev. 2009 Nov 25.

Implications of KRAS mutation status for the treatment of metastatic colorectal cancer.
Ciardiello F, Tejpar S, Papamichael D.
Target Oncol. 2009 Nov 14.

Treatment of the elderly colorectal cancer patient: SIOG expert recommendations.
D. Papamichael; R. Audisio; J.-C. Horiot; B. Glimelius; J. Sastre; E. Mitry; E. Van Cutsem; M. Gosney; C.-H. Kohne; M. Aapro 
Ann Oncol 2009;20(1):5-16

Concomitant gastric adenocarcinoma and stromal tumor in a woman with polymyalgia rheumatica.
Kountourakis P, Arnogiannaki N, Stavrinides I, Apostolikas N, Rigatos G.
World J Gastroenterol. 2008 Nov 21;14(43):6750-2.

Prognostic value of kallikrein-related peptidase 6 protein expression levels in advanced ovarian cancer evaluated by automated quantitative analysis (AQUA).
Kountourakis P, Psyrri A, Scorilas A, Camp R, Markakis S, Kowalski D, Diamandis EP, Dimopoulos MA.
Cancer Sci. 2008 Nov;99(11):2224-9.

Intestinal metastases from cervical carcinoma may be falsely attributed to radiation enteropathy.
V. Vassiliou, M. Pomoni, D. Kardamakis.
European Journal of Obstetrics, Gynecology and Reproductive Biology, 2008;137:118-127

Metastatic adenocarcinoma of parotid gland originating from the ampulla of Vater. Case report and review of the literature.
D Spyropoulou, V Vassiliou, V Tzelepi, M Kardari, AC Tsamandas, D Kardamakis.
International Journal of gastrointestinal Cancer, 2008;38:95-98.

Types of bone metastases in women with breast cancer undergoing systemic treatments.
V Vassiliou, D Kardamakis.
Medical Radiology Journal (Radiol Med) 2008;113(5):771-773

A case of osteonecrosis of the jaw in patient receiving chronic ibandronate treatment.
D Vomvas, V Vassiliou, D Kardamakis.
Journal BUON, 2008;13:441-442.

Clinical and radiologic response in patients with bone metastases managed with combined radiotherapy and bisphosphonates.
Vassiliou V, Kalogeropoulou C, Kardamakis D.
Journal of Surgical Oncology. 2008;98:567-568.

Challenges in treating older cancer patients: colon cancer.
D. Papamichael.
Ann Oncol 2008; 19 (suppl 7): vii104-vii108

Potential value of PTEN in predicting cetuximab response in colorectal cancer. An exploratory study.
Evangelia Razis, Evangelos Briasoulis,  Eleni Vrettou,  Dimosthenis V Skarlos,  Dimitrios Papamichael,  Ioannis Kostopoulos, Epaminontas Samantas, Ioannis Xanthakis, Mattheos Bobos, Eleni Galanidi, Maria Bai, Ioanna Gikonti, Alona Koukouma, Georgia Kafiri, Pavlos Papakostas, Konstantine T Kalogeras, Paris Kosmidis and George Fountzilas .
BMC Cancer 2008;  8:234

HLA Class II Alleles and the Presence of Circulating Epstein-Barr Virus DNA in Greek Patients with Nasopharyngeal Carcinoma.
Epaminondas Samantas, Angelos Nicolaou, Lemonia Skoura, Nicolaos Tselis, Nikolaos Zamboglou, George Fountzilas.Charisios Karanikiotis, Michail Daniilidis, Nikolaos Kariotis, Charalambos Bakogiannis, Theophanis Economopoulos, Samuel Murray, Demetris Papamichael.
Strahlenther Onkol. 2008;184:325–31

Merkel cell carcinoma of the skin: a retrospective study of 24 cases by the Hellenic Cooperative
Pectasides D, Papaxoinis G, Pectasides E, Galani H, Razi E, Katodrytis N, et al.
Oncology Group. Oncology. 2007;72:211–8. [PubMed]

Colon Cancer Adjuvant Therapy: Current Status.  CME Journal Gastroenterology.
Papamichael D. 
Hepatology & Nutrition 2007 8(1): 3-10

Prognostic factors and significance of the revised 6th edition of the AJCC classification in patients with locally advanced nasopharyngeal cancer.
Kalogera-Fountzila Anna, Karanicolas Demetrios, Katodritis Nikos, Samantas Epaminondas, Sarafopoulos Apostolos, Ikonomou Ippoliti, Zamboglou Nikolaos, Tselis Nikolaos, Dimitriadis Athanasios-Sokratis, Fountzilas George.
Strahlenther Onkol. 2006 Aug; 182(8): 458-466

Novel germline mutations in the APC gene of Cypriot patients with familial and sporadic adenomatous polyposis.
Hadjisavvas A, Papasavva D, Loizidou M, Malas S, Potamitis G, Christodoulou C, Pavlidis G, Papamichael D
Klonis C, Nasioulas G, Anastasiadou V, Kyriakou K.
Clin Genet 2006 May;69(5):404-9

Reply to ‘Lack of response of cetuximab plus oxaliplatin…’ by B. Vincenzi et al. Angela J Darby, Demetris Papamichael. 
Ann Oncol 28 November 2005

Platinum-based chemotherapy in metastatic breast cancer: the Leicester (U.K.) experience.
Decatris M, Sundar S, Sundar S, O'Byrne KJ
Clin Oncol (R Coll Radiol) 2005 Jun; 17(4): 249-257

Complementary role of helical CT cholangiography to MR cholangiography in the
evaluation of biliary function and kinetics.
Eracleous E, Genagritis M, Papanikolaou N, Kontou A, Prassopoullos P,
Chrysikopoulos H, Allan P, Gourtsoyiannis N
Eur Radiol. 2005 Jun 8; 1: [Epub ahead of print]

Induction Chemotherapy with Cisplatin, Epirubicin, and Paclitaxel (CEP),
Followed by Concomitant Radiotherapy and Weekly Paclitaxel for the Management of Locally Advanced Nasopharyngeal Carcinoma.
A Hellenic Cooperative Oncology Group Phase II Study.
Fountzilas G, Tolis C, Kalogera-Fountzila A, Karanikiotis C, Bai M,
Misailidou D, Samantas E, Athanassiou E, Papamichael D, Tsekeris P, Katodritis N, Nicolaou A, Plataniotis G, Makatsoris T, Papakostas P, Zamboglou N, Daniilidis J
Strahlenther Onkol. 2005 Apr; 181(4): 223-230

Endothelin-1 is a novel prognostic factor in non-small cell lung cancer.
Arun C, Decatris M, Hemingway DM, London NJ, O'Byrne KJ
Int J Biol Markers. 2004 Oct-Dec; 19(4): 262-267

Phase II trial of Oxaliplatin and 5-Fluorouracil/Leucovorin combination in
epithelial ovarian carcinoma relapsing within 2 years of platinum-based therapy.
Sundar S, Symonds RP, Decatris M, Kumar DM, Osman A, Vasanthan S, O'byrne KJ
Gynecol Oncol. 2004 Aug; 94(2): 502-508

Lack of pharmacokinetic interaction between 5-fluorouracil and oxaliplatin.
Joel SP, Papamichael D, Richards F, Davis T, Aslanis V, Chatelut E, Locke K,
Slevin ML, Seymour MT
Clin Pharmacol Ther. 2004 Jul; 76(1): 45-54

Description of the first two seemingly unrelated Greek Cypriot families with a
common C618R RET proto-oncogene mutation.
Neocleous V, Passalaris T, Spanou E, Kitsios P, Skordis N, Deltas CC.
Genet Test. 2004 Summer; 8(2): 163-168

Management of endocrine resistant breast cancer.
Sundar S, Decatris M, O'Byrne KJ
J Br Menopause Soc. 2004 Mar; 10(1): 16-23

Platinum-based chemotherapy in metastatic breast cancer: current status.
Decatris M, Sundar S, O'Byrne KJ
Cancer Treat Rev. 2004 Feb; 30(1): 53-81

Phase II study of irinotecan and mitomycin C in 5-fluorouracil-pretreated patients with advanced colorectal and gastric cancer.
Bamias A, Papamichael D, Syrigos K, Pavlidis N.
J Chemother. 2003 Jun; 15(3): 275-81

Patterns of clinical presentation, treatment, and outcome in patients with Waldenstrom's macroglobulinemia: a two-institution study.
Bjorkholm M, Johansson E, Papamichael D, Celsing F, Matthews J, Lister TA, Rohatiner AZ.
Semin Oncol. 2003 Apr; 30(2): 226-30

Adjuvant treatment of high-risk stage II breast cancer with doxorubicin followed by high-dose chemotherapy and autologous stem-cell transplantation: a single-institution experience with 132 consecutive patients.
Stemmer SM, Hardan I, Raz H, Adamou A, Inbar M, Gottfried M, Merrick Y, Cohen Y, Sulkes A, Ben-Baruch N, Pfeffer RP, Brenner HJ, Rizel S.
Bone Marrow Transplant. 2003 Apr; 31(8): 655-61.

BRCA2 germline mutations in Cypriot patients with familial breast/ovarian cancer.
Hadjisavvas A, Charalambous E, Adamou A, Christodoulou CG, Kyriacou K.
Hum Mutat 2003 Feb; 21(2): 171

Epidural metastasis in nasopharyngeal carcinoma.
Bagatzounis A , Erakleous E, Michaelides I.
Strahlenther Onkol 2003 Feb; 179(2): 123-8

Combined percutaneous and intraluminal radiotherapy for irresectable Klatskin tumors.
Schleicher UM, Staatz G, Alzen G, Andreopoulos D
Strahlenther Onkol, Vol 178, No 12 (2002): 682-687

Correlation between morphology, immunohistochemistry and molecular pathology in hereditary and sporadic breast cancer cases.
Hadjisavvas A, Mikellidou C, Zenios A, Zouvani I, Adamou A, Christodoulou Ch, Kyriacou K
Ultrastruct Pathol. 2002 Jul-Aug; 26(4): 237-44

Tumor volumetry as predictive and prognostic factor in the management of ovarian cancer. Andreopoulou E, Andreopoulos D, Adamidis K, Fountzila-Kalogera A, Fountzilas G, Dimopoulos MA, Aravantinos G, Zamboglou N, Baltas D, Pavlidis N
Anticancer Res 2002 May-Jun; 22 (3): 1903-8

Q356R and S1512I are BRCA1 variants that may be associated with breast cancer in a Cypriot family.
Hadjisavvas A, Adamou A, O'Dowd Phanis C, Todd CM, Kitsios P, Kyriacou K, Christodoulou CG
Oncol Rep 2002 Mar-Apr; 9(2): 383-6

Weekly paclitaxel as first-line chemotherapy and trastuzumab in patients with advanced breast cancer. A Hellenic Cooperative Oncology Group phase II study.
Fountzilas G, Tsavdaridis D, Kalogera-Fountzila A, Christodoulou CH, Timotheadou E, Kalofonos CH, Kosmidis P,
Adamou A, Papakostas P, Gogas H, Stathopoulos G, Razis E, Bafaloukos D, Skarlos D
Ann Oncol 2001 Nov; 12(11): 1545-51

Prognostic role of angiogenesis in colorectal cancer.
Papamichael D
Anticancer Res. 2001 Nov-Dec; 21(6B): 4349-53

BRCA1 germline mutations in Cypriot breast cancer patients from 26 families with family history.
Hadjisavvas A, Neuhausen SL, Hoffman MD, Adamou A, Newbold RF, Kyriacou KC, Christodoulou CG
Anticancer Res. 2001 Sep-Oct; 21(5): 3307-11

Feasibility and low toxicity of early radiotherapy after high-dose chemotherapy and autologous stem cell transplantation for patients with high-risk stage II-III and locally advanced breast carcinoma.
Stemmer SM, Pfeffer MR, Rizel S, Hardan I, Goffman J, Gezin A, Neumann A, Kitsios P, Alezra D, Brenner HJ
Cancer 2001 Jun 1; 91(11): 1983-91

Long-term effects on the intelligence of children treated for acute lymphoblastic leukemia.
Kolotas C, Daniel M, Demetriou L, Martin T, Kurek R, Tonus C, Gobel U, Schnabel T, Zamboglou N
Cancer Invest 2001; 19(6): 581-7

Palliative radiotherapy in recurrent head-and-neck tumors by a percutaneous superfractionated treatment schedule.
Schleicher UM, Andreopoulos D, Ammon J
Int J Radiat Oncol Biol Phys 2001 May 1; 50(1): 65-8

Intraoperative radiotherapy for pre-irradiated head and neck cancer.
Schleicher UM, Phonias C, Spaeth J, Schlondorff G, Ammon J, Andreopoulos D
Radiother Oncol 2001 Jan; 58(1): 77-81

A phase II study of combined intravenous and subcutaneous interleukin-2 in malignant pleural mesothelioma.
Mulatero CW, Penson RT, Papamichael D, Gower NH, Evans M, Rudd RM
Lung Cancer 2001 Jan; 31(1): 67-72

Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer.
de Gramont A, Figer A, Seymour M, Homerin M, Hmissi A, Cassidy J, Boni C, Cortes-Funes H, Cervantes A, Freyer G, Papamichael D, Le Bail N, Louvet C, Hendler D, de Braud F, Wilson C, Morvan F, Bonetti A
J Clin Oncol 2000 Aug; 18(16): 2938-47

Immunohistochemical versus molecular detection of RAK antigens in breast cancer.
Kyriacou KC, Iacovou F, Adamou A, Hadjisavvas A, Rakowicz-Szulczynska EM
Exp Mol Pathol 2000 Aug; 69(1): 27-36

A novel arginine vasopressin-neurophysin II mutation causes autosomal dominant neurohypophyseal diabetes insipidus and morphologic pituitary changes.
Skordis N, Patsalis PC, Hettinger JA, Kontou M, Herakleous E, Krishnamani MR, Phillips JA 3rd
Horm Res 2000; 53(5): 239-45

The postoperative adjuvant radiation therapy and radiochemotherapy for UICC stage II and III rectal cancer. A retrospective analysis.
Bagatzounis A , Willner J, Oppitz U, Flentje M
Strahlenther Onkol 2000 Mar; 176(3): 112-7

Improved detection of breast cancer nuclei using modular neural networks.
Schnorrenberg F, Tsapatsoulis N, Pattichis CS, Schizas CN, Kollias S, Vassiliou M, Adamou A, Kyriacou K
IEEE Eng Med Biol Mag 2000 Jan-Feb; 19(1): 48-63

The use of thymidylate synthase inhibitors in the treatment of advanced colorectal cancer: current status.
Papamichael D
Stem Cells 2000; 18(3): 166-75

The use of thymidylate synthase inhibitors in the treatment of advanced colorectal cancer: current status.
Papamichael D
Oncologist 1999; 4(6): 478-87

Radioprotection of human endothelial cells with amifostine.
Andreopoulos D , Schleicher UM, Cotarelo CL, Hand S, Ammon J
Strahlenther Onkol 1999 Nov;175 Suppl 4:34 -6

Epirubicin, cisplatin and oral UFT with leucovorin ('ECU'): a phase I-II study in patients with advanced upper gastrointestinal tract cancer.
Seymour MT, Dent JT, Papamichael D, Wilson G, Cresswell H, Slevin ML
Ann Oncol 1999 Nov; 10(11):1329-33

Radioprotection of human endothelial cells by sodium selenite.
Schleicher UM, Lopez Cotarelo C, Andreopoulos D, Handt S, Ammon J
Med Klin 1999 Oct 15; 94 Suppl 3:35-8

Immunocytoma: a retrospective analysis from St Bartholomew's Hospital-1972 to 1996.
Papamichael D , Norton AJ, Foran JM, Mulatero C, Mathews J, Amess JA, Bradburn M, Lister TA, Rohatiner AZ
J Clin Oncol 1999 Sep; 17(9):2847-53

Conventionally fractionated radiotherapy of glioblastoma multiforme. Results and analysis of possible influencing factors.
Schleicher UM, Andreopoulos D, Ammon J, Gilsbach J
Front Radiat Ther Oncol 1999; 33:166-73

Combined treatment of localized prostate cancer with HDR-Iridium 192 remote brachytherapy and external beam irradiation.
Andreopoulos D , Piatkowiak M, Krenkel B, Schleicher UM, Wolff JM
Strahlenther Onkol 1999 Aug;175(8):387-91

A new method for the placement of brachytherapy probes in paranasal sinus and nasopharynx neoplasms.
Kremer B, Klimek L, Andreopoulos D, Mosges R
Int J Radiat Oncol Biol Phys 1999 Mar 15;43(5):995-1000

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